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David R Freyer Selected Research

sodium thiosulfate

1/2022Sodium thiosulfate for prevention of cisplatin-induced hearing loss: updated survival from ACCL0431.
1/2020Prevention of cisplatin-induced ototoxicity in children and adolescents with cancer: a clinical practice guideline.
1/2018Sodium Thiosulfate and Cisplatin-Induced Hearing Loss.
1/2017Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial.

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David R Freyer Research Topics

Disease

30Neoplasms (Cancer)
03/2022 - 02/2006
10Hearing Loss (Hearing Impairment)
01/2022 - 01/2009
7Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022 - 03/2008
4Obesity
03/2022 - 12/2014
4Leukemia
01/2022 - 12/2014
3Second Primary Neoplasms (Neoplasms, Second)
01/2022 - 11/2008
3Cardiomyopathies (Cardiomyopathy)
01/2022 - 09/2012
3Ototoxicity
01/2020 - 07/2012
2Dyslipidemias (Dyslipidemia)
03/2022 - 05/2015
2Lymphoma (Lymphomas)
01/2022 - 08/2015
2Hematologic Neoplasms (Hematological Malignancy)
01/2021 - 06/2014
2Brain Neoplasms (Brain Tumor)
03/2016 - 06/2012
2Glioma (Gliomas)
01/2016 - 07/2012
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2015 - 09/2013
2Heart Failure
12/2014 - 06/2014
2Dyspnea (Shortness of Breath)
07/2014 - 08/2013
2Chronic Cough
07/2014 - 08/2013
1Prehypertension
03/2022
1Hypertension (High Blood Pressure)
03/2022
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2022
1Osteosarcoma (Osteogenic Sarcoma)
01/2022
1Hodgkin Disease (Hodgkin's Disease)
01/2022
1Stroke (Strokes)
01/2022
1Tinnitus
10/2021
1Melanoma (Melanoma, Malignant)
06/2021
1Insulin Resistance
01/2021
1Hepatoblastoma
01/2020
1Chronic Disease (Chronic Diseases)
11/2017
1Vitamin D Deficiency
10/2017
1Metabolic Bone Diseases (Osteopenia)
10/2017
1Neutropenia
01/2017
1Sensorineural Hearing Loss
03/2016
1Neurofibromatosis 1 (Neurofibromatosis Type I)
01/2016
1Iron Overload
09/2015
1Hemoglobinopathies
09/2015
1Residual Neoplasm
12/2014
1Left Ventricular Dysfunction
12/2014
1Hemochromatosis (Bronze Diabetes)
09/2014
1Pneumonia (Pneumonitis)
08/2013
1Interstitial Lung Diseases (Interstitial Lung Disease)
08/2013
1Congenital Abnormalities (Deformity)
08/2013
1Glycogen Storage Disease Type II (Pompe's Disease)
03/2009
1Weight Loss (Weight Reduction)
11/2008
1Cachexia
11/2008
1Hyperlipidemias (Hyperlipidemia)
11/2008
1Infections
06/2004

Drug/Important Bio-Agent (IBA)

9Cisplatin (Platino)FDA LinkGeneric
01/2022 - 01/2009
4sodium thiosulfateFDA Link
01/2022 - 01/2017
4PlatinumIBA
10/2021 - 06/2012
4AnthracyclinesIBA
12/2014 - 09/2012
3IronIBA
09/2015 - 10/2012
3Biomarkers (Surrogate Marker)IBA
12/2014 - 06/2014
2Doxorubicin (Adriamycin)FDA LinkGeneric
03/2022 - 01/2022
2Dexrazoxane (Zinecard)FDA LinkGeneric
01/2022 - 08/2015
2Carboplatin (JM8)FDA LinkGeneric
01/2016 - 07/2012
2Oxygen (Dioxygen)IBA
07/2014 - 08/2013
1AdiponectinIBA
01/2021
1Biological ProductsIBA
12/2018
1Cholecalciferol (Vitamin D3)FDA Link
10/2017
1hydroxide ionIBA
10/2017
1CalciumIBA
10/2017
1Vitamin DFDA LinkGeneric
10/2017
1VitaminsIBA
10/2017
1AntioxidantsIBA
01/2017
1Vincristine (Oncovin)FDA LinkGeneric
01/2016
1antiarrhythmic peptide (AAP)IBA
05/2015
1milk-derived factorIBA
12/2014
1Indicators and Reagents (Reagents)IBA
12/2014
1Galectin 3 (LGALS3)IBA
12/2014
1Brain Natriuretic Peptide (Natrecor)FDA Link
12/2014
1Troponin T (Troponin T1)IBA
12/2014
1pro-brain natriuretic peptide (1-76)IBA
12/2014
1Platinum Compounds (Compounds, Platinum)IBA
06/2012
1human GAA protein (Myozyme)FDA Link
03/2009
1Hydrocortisone (Cortisol)FDA LinkGeneric
11/2008
1Cyproheptadine (Periactin)FDA Link
11/2008
1Megestrol Acetate (Borea)FDA LinkGeneric
11/2008
1Immunoglobulin E (IgE)IBA
06/2004
1Immunoglobulin M (IgM)IBA
06/2004
1Immunoglobulin G (IgG)IBA
06/2004
1Immunoglobulin A (IgA)IBA
06/2004

Therapy/Procedure

16Therapeutics
01/2022 - 02/2006
12Drug Therapy (Chemotherapy)
01/2021 - 01/2009
5Aftercare (After-Treatment)
01/2022 - 02/2015
2Stem Cell Transplantation
01/2022 - 11/2009
2Cranial Irradiation
10/2021 - 06/2012
2Patient Transfer (Patient Dumping)
11/2010 - 05/2008
1Heart Transplantation (Grafting, Heart)
01/2022
1Immunotherapy
06/2021
1Caloric Restriction
01/2021
1Ambulatory Care (Outpatient Care)
10/2006